R&D at THE SERVICE OF HEALTH
BiophysiumOriginal articles

Key role of endothelium in the eNOS-dependent cardioprotection with exercise training
Key role of endothelium in the eNOS-dependent cardioprotection with exercise trainingFarah C, Nascimento A, Bolea G, Meyer G, Gayrard S, Lacampagne A, Cazorla O, Reboul C.J Mol Cell Cardiol. 2017 Jan;102:26-30. doi: 10.1016/j.yjmcc.2016.11.008. Epub 2016 Nov 17....
Exercise-induced cardioprotection: a role for eNOS uncoupling and NO metabolites
Exercise-induced cardioprotectionA role for eNOS uncoupling and NO metabolites. Farah C, Kleindienst A, Bolea G, Meyer G, Gayrard S, Geny B, Obert P, Cazorla O, Tanguy S, Reboul C.Basic Res Cardiol. 2013 Nov;108(6):389. doi: 10.1007/s00395-013-0389-2. Epub 2013 Oct 9....
Lipid protection by polyphenol-rich apple matrices is modulated by pH and pepsin in in vitro gastric digestion
Lipid protection by polyphenol-rich apple matrices is modulated by pH and pepsin in in vitro gastric digestion.Bolea G, Ginies C, Vallier MJ, Dufour C. Food Funct. 2019 Jul 17;10(7):3942-3954. doi:10.1039/c9fo00705a. PMID: 31199415.
Digestive n-6 Lipid Oxidation, a Key Trigger of Vascular Dysfunction and Atherosclerosis in the Western Diet: Protective Effects of Apple Polyphenols
Digestive n-6 Lipid Oxidation, a Key Trigger of Vascular Dysfunction and Atherosclerosis in the Western Diet : Protective Effects of Apple Polyphenols. Bolea G, Philouze C, Dubois M, Risdon S, Humberclaude A, Ginies C, Charles AL, Geny B, Reboul C, Arnaud C, Dufour C,...
Congress communications

Oxydation des lipides polyinsaturés lors de la digestion et effet sur la fonction endothéliale et l’athérosclérose
Oxydation des lipides polyinsaturés lors de la digestion et effet sur la fonction endothéliale et l’athéroscléroseModulation par la consommation de pomme. Oral communication. Conference TerSys Oxidative stress, June 26, 2017, Avignon). Bolea G, Philouze C, Dubois M,...
Apple procyanidins decrease oxidation of dietary lipids in the in vitro gastrointestinal digestion model of a Western meal
Apple procyanidins decrease oxidation of dietary lipids in the in vitro gastrointestinal digestion model of a Western meal.French congress of Cardiology, Basic and clinical research, Nantes, April to 6-8, 2017. Bolea G, Ginies C, Meyer G, Dufour C.
Lipid oxidation and its inhibition by apple polyphenols in static and dynamic in vitro digestion systems
Lipid oxidation and its inhibition by apple polyphenols in static and dynamic in vitro digestion systemsPoster communication. 5th International Conference on Food Digestion, Rennes, April to 4-6, 2017. Bolea G, Goupy P, Ginies C, Dufour C.
Les polyphénols de pomme réduisent la dysfonction endothéliale
Les polyphénols de pomme réduisent la dysfonction endothélialeLes polyphénols de pomme réduisent la dysfonction endothéliale et l’athérosclérose après un régime chronique de type Western chez les souris ApoE-/-. Oral and poster communication. French congress of...
Apple polyphenols decrease endothelial dysfunction and atherosclerosis after chronic Western diet in a ApoE mouse model
Apple polyphenols decrease endothelial dysfunction and atherosclerosis after chronic Western diet in a ApoE mouse modelOral communication. 2nd Conference on food bioactives health, Lisbonne, September 26-28, 2018. Bolea G, Philouze C, Dubois M, Humberclaude A, Ginies...
Apple polyphenols decrease endothelial dysfunction and atherosclerosis
Apple polyphenols decrease endothelial dysfunction and atherosclerosis in ApoE mice fed with chronic Western diet.Poster communication. French congress of Cardiology, Basic and clinical research, Lille, April to 1-3, 2019. Bolea G, Philouze C, Risdon S, Dubois M,...
TOTUM-854 prevents L-NAME-induced arterial hypertension in mice
TOTUM-854 prevents L-NAME-induced arterial hypertension in miceBolea G, Ripoche D, Meyer G, Lejoubiuox F, Michaux A, Otero YF, Peletier SL, Sirvent P, Reboul C. European Society of Hypertension and the International Society of Hypertension held from April 11 to 14,...
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Biophysium is happy to be a new member of the Clubster NSL competitiveness hub
Biophysium is happy to be a new member of the French Cardiology Society
Biophysium is happy to be a new member of the French Cardiology Society. We will also be present in the spring of cardiology 2022 (Tours, France).
Biophysium is happy to be a new member of the French Deeptech community
Biophysium is happy to be a new member of the EUROBIOMED competitiveness hub
In vitro Glycemic index : new method in collaboration with IG balance (Avignon University)
If you wish to evaluate the in vitro glycemic index of your food product, contact us. We have developed a new method based on the latest scientific recommendations in collaboration with IG Balance.