Analytics lab


    Analytical microscopy methods are essential tools to support your development or testing program in pre-clinical or clinical studies. Combining solid scientific knowledge and our different protocols with state-of-the-art technologies, we allow you to evaluate in a comprehensive manner:


                 ° Location of oxidative stress: cytosol, mitochondrial, ER

                 ° Calcium fluorescence: cytosol, mitochondrial, ER

                 ° Nitro-oxidative stress

                 ° Production of NO (nitric oxide)

                 ° Mitochondrial fission/fission (mitotracker)

                 ° Membrane potential


     Our tools of confocal microscopy and electron microscopy, allow us to develop customized analyses.


Chemical analysis


Strong scientific knowledge of Biophysium’s analytical chemistry team with state-of-the art technologies allows  feasibility studies and set-up and validates new testing methods. All studies are performed in accordance with GLP. Tools of our

analytical platform are:

                    ° UV/Vis spectrophotometer

                    ° HPLC equipped with UV, fluorimeter

                    ° UPLC equipped with UV and fluorimeter detectors

                    ° GC equipped with FID and MS detector

                    ° Triple TOF mass spectrometer

                    ° Triple Quadrupole mass spectrometer

     Our analyzes will allow you to obtain a strong method development/transfer and validation, testing formulation and stability, bioaccessibility, biodisponibility, and metabolite identification. Our analyses are performed in diet and all biological fluids and tissues.

    Pharmacokinetic/Toxicokinetic (PK/TK) Analysis

        PK/TK samples analysis are performed in all biological fluids and tissues. Biophysium support your pre-clinical and clinical development programs on metabolism or pharmaceuticals studies. Because the choice of the route of administration  depend on the physical and chemical characteristics of the test substance, Biophysium is able to administrate your product by  different routes: 

                                     ° Oral

                                     ° Intra-venous

                                     ° Continuous intra-venous infusion

                                     ° Subcutaneous

                                     ° Dermal

                                     ° Intra-dermal

                                     ° Intramuscular

                                     ° Intra-peritoneal

                                      ° Intra-duodenal

                                      ° Intra-hepatic

                                      ° Intra-vesicular

                                      ° Ocular

                                      ° Intra-articular






    Analytical chemistry